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Understanding Proctalgia Fugax and Its Causes

Updated: Jun 19, 2024



Proctalgia fugax is derived from two Latin words: "proctalgia" (proctos meaning rectum and algia meaning pain) and "fugax" (meaning fleeting or transitory). This condition is characterized by sudden, severe rectal pain that lasts from a few seconds to a few minutes. The exact cause is not well understood, but it is believed to be related to muscle spasms in the rectal or anal region. Factors such as stress, certain foods, and bowel movements can trigger episodes. While the condition is benign, it can be distressing and disruptive.

References:

  • NHS. (n.d.). Proctalgia Fugax.

  • UpToDate. (n.d.). Proctalgia Fugax and Levator Ani Syndrome. Retrieved from UpToDate.


Can Mast Cell Activation Syndrome (MCAS) Lead to Proctalgia Fugax?

Mast Cell Activation Syndrome (MCAS) is a disorder where mast cells release excessive histamine and other chemicals, leading to various symptoms, including muscle spasms and increased pain sensitivity. These effects can potentially contribute to conditions like proctalgia fugax. Histamine release from mast cells can cause smooth muscle contraction and localized inflammation, which may trigger the sudden rectal pain seen in proctalgia fugax.

References:

  • Afrin, L. B., Butterfield, J. H., & Raithel, M. (2016). Presentation, Diagnosis, and Management of Mast Cell Activation Syndrome. In Mast Cells: Phenotypic Features, Biological Functions and Role in Immunity (pp. 155-166). Springer, Cham.

  • American Academy of Allergy, Asthma & Immunology. (n.d.). Mast Cell Activation Syndrome (MCAS).


Linking the Two:

Recent insights suggest a potential link between MCAS and proctalgia fugax. The excessive histamine release in MCAS can cause muscle spasms and heightened pain sensitivity, potentially leading to the development of proctalgia fugax. Managing MCAS with antihistamines, mast cell stabilizers, and dietary changes may help alleviate the symptoms of proctalgia fugax. If you experience persistent rectal pain, consulting with specialists can provide a comprehensive approach to diagnosis and treatment.


Manage Proctalgia Fugax by addressing MCAS, here’s a link to my blog on MCAS. Manage MCAS



References:

  • Castells, M., Matito, A., & Escribano, L. (2015). Diagnosis and Management of Mast Cell Activation Syndrome (MCAS). Advances in Therapy, 32(5), 368-377.

  • Cleveland Clinic. (n.d.). Proctalgia Fugax. Retrieved from Cleveland Clinic.



By Dr Purity Carr

GP&Menopauae Doctor

Harvey, WA


 
 
 

1 Comment

Hayley Leske
Hayley Leske
Jun 18, 2024

I have been suffering with this for about 1 year. It takes my breath away completely. The pain reminds me alot of labour contractions. You feel it building to a peak and then fades off. It can be a long few minutes that often leave me in tears. I'm glad it's being spoken about.

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Welcome to Purity Health Women’s Menopause and Wellbeing Centre™

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At Purity Health, we believe in living life to the fullest. Dr Purity Menopause Clinic, in association with Samy Medical Group, is dedicated to providing safe, evidence based information and care in perimenopause, menopause, histamine related conditions, and metabolic health.

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We recognise that there are many myths and misunderstandings surrounding menopause and Hormone Replacement Therapy, HRT. One commonly repeated belief is that oestrogen causes breast cancer. This is an oversimplification and does not reflect the full body of evidence.

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Here is the truth.

At Dr Purity Carr Menopause Clinic, we are committed to providing accurate information and personalised care.

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Extensive evidence shows that for women within 10 years of menopause or under the age of 60, the benefits of HRT generally outweigh the risks.

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For women who start HRT during perimenopause or within 10 years of menopause, there is often no need to stop purely based on age. Ongoing use should be individualised and guided by clinical review.

Even for women who are further beyond menopause or over 60, starting HRT may still be considered under the guidance of a knowledgeable practitioner, with careful assessment of risks and benefits.

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A Broader Approach to Women’s Health

Dr Purity is a General Practitioner with a special interest in menopause care, taking a holistic, systems based approach to women’s health.

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In addition to menopause, her work now includes:

Hormone health, including perimenopause and menopause
Histamine related conditions, including suspected mast cell activation patterns
Metabolic health, including weight management, insulin resistance, and inflammation
The interaction between hormones, the immune system, and the nervous system

Many women experience symptoms that do not sit neatly within one system. Hormones do not operate in isolation. There is often an overlap between hormonal changes, histamine activity, and metabolic dysfunction. This integrated approach allows for a deeper understanding of symptoms such as fatigue, anxiety, poor sleep, weight gain, brain fog, and chronic inflammation.

 

Dr Purity’s Focus on Care

Dr Purity focuses specifically on menopause, histamine balance, and metabolic health. She works to identify underlying drivers of symptoms and supports women through evidence based, personalised care.

Please note that Dr Purity does not replace your general practitioner. The experienced doctors at Samy Medical, part of the same medical system as Purity Health, are available to manage your broader healthcare needs.

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