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Differences Between Body-Identical and Bio-Identical HRT in Australia


Differences Between Body-Identical and Bio-Identical HRT in Australia


Body-Identical HRT:



Definition: Hormones that are chemically identical to those naturally produced by the human body, available as standard pharmaceutical products.


Regulation: Regulated by the Therapeutic Goods Administration (TGA) to ensure safety and efficacy.


Common Forms: Includes estradiol patches, gels, and micronized progesterone capsules (e.g., Estradot patches, Prometrium capsules).


Availability: Widely available through regular pharmacies with a prescription.


Bio-Identical HRT:



Definition: Refers to compounded hormones that are chemically identical to human hormones but are custom-made to match individual needs.


Regulation: Individual hormones are regulated, but custom-compounded formulations are not subject to the same rigorous testing as standard products.


Custom Compounding: Tailored to specific hormonal requirements of the patient, offering more personalized treatment options.


Common Forms: May include creams, gels, lozenges, or troches compounded in pharmacies.


Key Differences in Australia:


Regulation and Quality Control: Body-identical HRT products are strictly regulated by the TGA, ensuring consistent quality and dosage. Compounded bio-identical HRT formulations may have variability in quality and efficacy due to less stringent regulation.


Standardization vs. Personalization: Body-identical HRT offers standardized dosing and forms for easier management and monitoring, while bio-identical HRT provides personalized treatment but may require more careful monitoring and adjustment.


In summary, body-identical HRT in Australia is generally considered more reliable due to stringent regulation and standardization, while bio-identical HRT offers a personalized approach with potentially less consistency in quality and dosage.


Further reading Australasian Menopause Society link



Dr Purity Carr

GP& Menopause Doctor

Harvey, WA, 6220

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