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Why HRT works Really well for Menopausal Depression & Anxiety, PMS, PMDD

Updated: Jun 14




Comparing estrogen-based treatments to antidepressants involves considering various factors, and it's essential to recognize that these treatments may have different mechanisms of action. Here are some points of comparison:

Mechanism of Action:

  • Antidepressants: Antidepressant medications work by influencing the levels of neurotransmitters (such as serotonin, norepinephrine, and dopamine) in the brain. They help regulate mood by affecting the communication between nerve cells.

  • Estrogen: Estrogen, on the other hand, may have more indirect effects on mood. It can influence neurotransmitter levels, promote neuroplasticity, and have anti-inflammatory effects. The mechanisms by which estrogen affects mood are complex and not fully understood.

  • Antidepressants: Antidepressants are specifically designed to treat depression and, in some cases, anxiety disorders. They are often prescribed for individuals with diagnosed mood disorders.

  • Estrogen: Estrogen may be used in certain cases to manage mood symptoms associated with hormonal fluctuations, such as those occurring during the menstrual cycle or menopause. It's not typically prescribed solely for depression or anxiety.

  • Antidepressants: Antidepressants can have a range of side effects, including nausea, insomnia, weight changes, sexual dysfunction, and others. The specific side effects depend on the type of antidepressant and individual response.

  • Estrogen: Estrogen therapy may be associated with its own set of side effects, including an increased risk of blood clots, cardiovascular issues, and breast cancer. The risks and benefits of estrogen therapy should be carefully considered, especially in the context of menopausal hormone therapy.

  • Antidepressants: Individual responses to antidepressants can vary significantly. It may take some time to find the right medication and dosage, and adjustments may be needed based on the individual's response and any side effects.

  • Estrogen: Similarly, individual responses to estrogen therapy can vary. Some individuals may experience improvements in mood, while others may not respond as favorably.

  • Antidepressants: Antidepressants are commonly prescribed for both men and women and are not specific to gender.

  • Estrogen: Estrogen-based treatments, such as hormone replacement therapy, are typically used in women, especially during menopause, to manage symptoms associated with hormonal changes.

By Dr Purity Carr

GP and menopause Doctor

Harvey , WA

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